Will There Be a Vaccine to Prevent HCV Infection?

Will there be a vaccine to prevent HCV infection?

Prevention of hepatitis C virus (HCV) infection by vaccination has been a priority since discovery of the virus and the need has not diminished over the past 25 years. Infection rates are increasing in developed countries because of intravenous drug use. Reducing transmission will be difficult without a vaccine to prevent persistence of primary infections, and also secondary infections that may...

Will He Be There?

This paper focuses on an unsettling example of experimental labour - the Human Landing Catch (HLC). The HLC is a cheap and reliable technique to produce data on mosquito densities in a defined area. It requires only a human volunteer to sit over night with his legs exposed, a headlamp to spot mosquitoes, and a rubber tube and plastic cup to catch them as they come to feed on him. The HLC formed...

Strategies of vaccine production against COVID-19: when will an effective vaccine be produced?

There is a strong consensus globally that production of an effective vaccine against SARS-CoV-2 is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. In this paper, we review vaccine candidate against COVID-19 and also cha...

There Will Never Be Another You.

“There will be blood” from fibroblasts

The blood system is continuously replenished from a rare population of hematopoietic stem cells (HSCs) that balance self-renewal and differentiation. It is believed that HSCs emerge during embryogenesis from a population of hemogenic endothelial cells at sites like the aorta-gonad-mesonephros (AGM) region and placenta. Transplantation of HSCs is a widely utilized cell therapy for a range of gen...